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Best Practices For State Of The Art Hormone Testing

  1. Meeran K et al. Br J Clin Pract (1993) 47(5): 246-7. | http://www.ncbi.nlm.nih.gov/pubmed?term=8292469
  2. Tissue content of hydroxyestrogens in relation to survival of breast cancer patients. Castagnetta LA, Granata OM, Traina A, Ravazzolo B, Amoroso M, Miele M, Bellavia V, Agostara B, Carruba G.  Clin Cancer Res. 2002 Oct;8(10):3146-55. http://www.ncbi.nlm.nih.gov/pubmed?term=12374682
  3. Comparison of Liquid Chromatography-Tandem Mass Spectrometry, RIA, and ELISA Methods for Measurement of Urinary Estrogens. Jessica M. Faupel-Badger, Barbara J. Fuhrman, Xia Xu, Roni T. Falk, Larry K. Keefer, Timothy D. Veenstra, Robert N. Hoover, Regina G. Ziegler. Cancer Epidemiol Biomarkers Prev; 19(1); 292–300. | http://www.ncbi.nlm.nih.gov/pubmed?term=20056650
  4. Comparison of estrogens and estrogen metabolites in human breast tissue and urine. Emanuela Taioli, Annie Im, Xia Xu, Timothy D Veenstra, Gretchen Ahrendt, Seymour Garte. Reproductive Biology and Endocrinology 2010, 8:93. http://www.ncbi.nlm.nih.gov/pubmed?term=20678202
  5. Estrogen Hydroxylation—The Good and the Bad, Daniel W. Sepkovic and H. Leon Bradlow. Steroid Enzymes and Cancer: Ann. N.Y. Acad. Sci. 1155: 57–67 (2009). | http://www.ncbi.nlm.nih.gov/pubmed?term=19250192
  6. Breast Cancer Research and Treatment, 2002, 72:139-143
  7. J Natl Cancer Inst, 1999, 12:1067-72
  8. Vining RF, et al. Ann Clin Biochem (1983) 20:329-35 | http://www.ncbi.nlm.nih.gov/pubmed?term=6316831
  9. Aadal-Eriksson E, et al. Clin Chem Lab Med(1998)36(4):215-222 | http://www.ncbi.nlm.nih.gov/pubmed?term=9638346
  10. Gozansky WS, et al. Clin Endocrin (2005) 63:336-341. | http://www.ncbi.nlm.nih.gov/pubmed?term=16117823
  11. Wren BG, et al. Lancet (1999) 354: 1447-8.
  12. Zorn RZ, et al. Fertility and Sterility 1984 Feb;41(2):248-53.| http://www.ncbi.nlm.nih.gov/pubmed?term=6698219
  13. O’Leary P, et al. Clin Endo (2000) 53:615-620 | http://www.ncbi.nlm.nih.gov/pubmed?term=11106923
  14. Webley GE, Edwards R. Ann Clin Biochem (1985) 22:579-585.2-726. | http://www.ncbi.nlm.nih.gov/pubmed?term=4073790
  15. http://health.allrefer.com/pictures-images/skin-layers.html
  16. Human Erythrocyte Membrane Uptake of Progesterone and Chemical Alterations.  Devenuto F, et al. Biochem. Biophys. Acta  (1969) 193:36-47.
  17. Lemon, HM. Cancer Res 35 (1975): 1341-1353. | http://www.ncbi.nlm.nih.gov/pubmed?term=123480
  18. Lemon HM, et al.  Cancer 63(9) (1989): 1685-1691.
  19. Lemon H, Wotiz H, Parsons L, Mozden P. Reduced estriol secretion in patients with breast cancer prior to endocrine therapy.JAMA. 1966;196:112-120..
  20. Lemon, HM. Acta Endocrinol (Copenh) 1980;233:S17-S27.
  21. IBL-Hamburg

Trust Your Gut Feelings

  1. Neirinckx RD, Canning LR, Piper IM, et al. Technetium 99m d,l-HM-PAO: a new radiopharmaceutical for SPECT imaging of regional cerebral perfusion. J Nucl Med 1987; 28:191—202. | http://www.ncbi.nlm.nih.gov/pubmed?term=3492596
  2. HM-PAO package insert. Amersham Canada Ltd., 1986.
  3. Hung CY, Volkert WA, Holmes RA: A kinetic analysis of Tc-99m-d,l-HM-PAO: decomposition in aqueous media [Abstract]. JNuclMed 1987; 28:593.4.Marianne J. Legato, John P. Bilezikian - 2004 - 1245 pages Bennink etal [91,95]
  4. National Institutes of Health, U.S. Department of Health and Human Services. Opportunities and Challenges in Digestive Diseases Research: Recommendations of the National Commission on Digestive Diseases. Bethesda, MD: National Institutes of Health; 2009. NIH Publication 08–6514.
  5. Everhart JE, ed. The Burden of Digestive Diseases in the United States. Bethesda, MD: National Institute of Diabetes and Digestive and Kidney Diseases, U.S. Dept of Health and Human Services; 2008. NIH Publication 09–6433.
  6. Kozak LJ, Owings MF, HallMJ, National Hospital Discharge Survey 2002 annual summary with detailed diagnosis and procedure data.  National Center for Health Statistics  Vital Health Stat 2005;13(158)
  7. Everhart JE, ed. The Burden of Digestive Diseases in the United States. Bethesda, MD: National Institute of Diabetes and Digestive and Kidney Diseases, U.S. Dept of Health and Human Services; 2008. NIH Publication 09–6433.
  8. Bacterial overgrowth link est. 1990
  9. Am  J Gastro 2000; 95:3503-06
  10. Page 192 in: Elizabeth D Agabegi;  Agabegi, Steven S. (2008). Step-Up to Medicine (Step-Up Series).
  11. Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-7153-6.
  12. HealthQuest, Inc. Nutritional
  13. William D. Chey, MD; Brennan Spiegel, MD Authors and Disclosures Posted: 07/02/2010; Clin Gastroenterol Hepatol. 2010;8(6):480-482. © 2010 AGA Institute
  14. Gastroenterology. 1985 Oct;89(4):894-913.Sarna SK Cyclic motor activity; migrating motor complex: 1985.
  15. APS 1992 Response of migrating motor complex to variation of fasting intraluminal content D Smith, B Waldron, FC Campbell  | http://www.ncbi.nlm.nih.gov/pubmed?term=1415711
  16. McKee DP, Quigley FM, Intestinal Motility  in Irritable Bowel Syndrome; is IBS a motility d/o 1993;38 1761-1772,1773-1782
  17. Camilleri M. Disorders of gastrointestinal motility. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 138
  18. Malin, M., Suomalainen, H. Saxelin, M. and Isolauri, E. 1996. Promotion of IgA immune response in patients with Crohn's disease by oral bacteriotherapy with Lactobacillus GG. Ann. Nutr. Metabolism. 40:137-145. |  http://www.ncbi.nlm.nih.gov/pubmed?term=8862696
  19. Small Intestinal Bacterial Overgrowth (SIBO) Medical Author: Dennis Lee MD Medical Editor: Jay W Marks MD
  20. Mark Pimentel, MD Bacteria – the missing link in treating irritable bowel syndrome
  21. “Why Stomach Acid is Good for You: Natural Relief from Heartburn, Indigestion, Reflux and GERD” Jonathan Wright MD
  22. Isolauri E. 1996. Studies on Lactobacillus gg in food hypersensitivity disorders Nutrition Today 31 1:28S-31S
  23. Salimen S, isolauri E, Salimen S 1996.  Clinical uses of probiotics for stablilizing the gut mucosal barrier; successful strains and future challenges.  Antonie Van Leeuenhoek 70: 347-358 | http://www.ncbi.nlm.nih.gov/pubmed?term=8992950
  24. Salimen S and M Saxelin 1996. Comparison of successful probiotic strains  Nutrition Today 31 (6) Supplement 1:32-34
  25. American Journal of Gastroenerology July 2005
  26. Gusland m, Giollo P Raffele University Hospital, Milan Italy EurJ Gastroenterol Hepatol. 2003 jun;15(6)697-8
  27. Bennet RG, Gorbach SL Goldin BR, Chang, Lasughon BE Green Bourgouh and Bartlett 1996 Treatment of relapsing diarrhea with lactobacillus gg. Nutrition today 31 35s-38s
  28. Gorbach SL. 1996. Efficacy of Lactobacillus in treatment of acute diarrhea. Nutrition Today 31(6) Supplement 1:19S-23S.
  29. Heck JE, and Cohen MB. 1993. Traveler's diarrhea. American Family Physician. 48(5):793.
  30. DuPont HL. 1997. Lactobacillus GG in prevention of traveler's diarrhea: an encouraging step. J. Travel Med.
  31. Goldin BR 1996 The metabolic activity of the intestinal microflora and its role in colon cancer:  lactobacillus and other factors that alter intestinal metabolic activity . Nutrition today 31(6) 24S-27s
  32. Gorbach SL. 1990. Lactic Acid bacteria and human health ANN MED. 22:37-41, | http://www.ncbi.nlm.nih.gov/pubmed?term=2109988
  33. Salminen S Tanaka R 1996. Role of cultured probiotic bacteria in gut health and disease IDF Nutrition 5:32-34
  34. Environmental Health NOV 2005
  35. Dr ZVI Weizman, Soroka Medical Center in Beer-Sheva, Israel
  36. Elmer GW, Surawicz CM, and McFarland LV. 1996. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. JAMA, 275:870-876. | http://www.ncbi.nlm.nih.gov/pubmed?term=8596226
  37. Swiss National Accident Insurance Institute Lucerne Switzerland
  38. Supported by the Academy of Finland, the funding of Turku University Central.
    Reprint requests: Mrs Minna Rinne, University of Turku, Functional Foods Forum, Itäinen Pitkäkatu 4A, 5th floor, FIN-20520 Turku, Finland.
  39. Centers for Disease Control
  40. Journal of Infection Control March/2007)
  41. Burton Goldberg Group Alternative Medicine;  the definitive guide, future med. Pub. WA 1993,p589
  42. ConsumerLab.com

Basic Endocrine Anatomy And Physiology

  1. Melmed: Williams Textbook of Endocrinology, 12th ed  Copyright 2011
  2. Rakel:  Textbook of Family Medicine, 8th ed.  Copyright 2011
  3. Tortora: Principles of Anatomy and Physiology, 5th ed Copyright 1987
  4. Koefoed P, Brahm J. BiochimBiophysActa. 1994 Oct 12;1195(1):55-62. | http://www.ncbi.nlm.nih.gov/pubmed?term=7918566

Adrenal Fatigue to Adrenal Fitness

  1. Lawrence Jeff Johnson -- the chief labor market economist. | http://archives.cnn.com/2001/CAREER/trends/08/30/ilo.study/.  August 31, 2001 Posted: 2:07 AM EDT (0607 GMT)
  2. Bureau of Labor statistics June 2011 http://www.bls.gov/news.release/atus.nr0.htm
  3. Psychoneuroendocrinology. 2011 Oct 31. [Epub ahead of print] Effects of prolonged stress on salivary cortisol and dehydroepiandrosterone: A study of a two-week teaching practice. Izawa S, Saito K, Shirotsuki K, Sugaya N, Nomura S. http://www.ncbi.nlm.nih.gov/pubmed?term=22047956
  4. E. Ronald de Kloet, et al. Brain Corticosteroid Receptor Balance in Health and Disease
    Endocrine Reviews 1998 19: 269-301; doi:10.1210/er.19.3.269 | http://www.ncbi.nlm.nih.gov/pubmed?term=9626555
  5. Psychoneuroendocrinology. 2006 Nov;31(10):1164-80. Epub 2006 Oct 19.
  6. Daytime cortisol and stress reactivity in the offspring of parents with bipolar disorder.
  7. Ellenbogen MA, Hodgins S, Walker CD, Couture S, Adam S.
  8. J Wilson N.D., D.C., PhD. Adrenal Fatigue, The 21st Century Stress Syndrome
  9. Review of Medical Physiology 17th edition. Ganong, William F., Appleton & Lange
  10. Speroff. Clinical Gynecologic Endocrinoloty and Infertility. 7th Edition 2005
  11. Development of the human adrenal zona reticularis: morphometric and immunohistochemical studies from birth to adolescence. Hui XG, Akahira J, Suzuki T, Nio M, Nakamura Y, Suzuki H, Rainey WE, Sasano H. J Endocrinol. 2009 Nov;203(2):241-52. Epub 2009 Sep 1.
  12. Control of Adrenal Androgen Secretion*LAWRENCE N. PARKER AND WILLIAM D. ODELL Endocrine Reviews Fall 1980 vol. 1 no. 4 392-410
  13. The hormonal pathway to cognitive impairment in older men. Maggio M, et al. J Nutr Health Aging. 2012;16(1):40-54. | http://www.ncbi.nlm.nih.gov/pubmed?term=22238001
  14. Effects of prolonged stress on salivary cortisol and dehydroepiandrosterone: A study of a two-week teaching practice. Izawa S, et al. Psychoneuroendocrinology. 2011 Oct 31. [Epub ahead of print] Sheng Li Ke Xue Jin Zhan. 2006 Oct;37(4):335-8. http://www.ncbi.nlm.nih.gov/pubmed/22047956
  15. [Functions and mechanisms of dehydroepiandrosterone in nervous system]. [Article in Chinese] Xie L, Sun HY, Gao J, Liao H. http://www.ncbi.nlm.nih.gov/pubmed?term=17262968
  16. Dehydroepiandrosterone (DHEA)--a precursor steroid or an active hormone in human physiology. Traish AM, et al. J Sex Med. 2011 Nov;8(11):2960-82; quiz 2983. doi: 10.1111/j.1743-6109.2011.02523. | http://www.ncbi.nlm.nih.gov/pubmed?term=22032408
  17. Horm Res. 2004;62 Suppl 3:110-4. Adrenopause. Nawata H, et al Nawata H, Yanase T, Goto K, Okabe T, Nomura M, Ashida K,  | http://www.ncbi.nlm.nih.gov/pubmed/15539809
  18. Clin Exp Rheumatol. 2011 Sep-Oct;29(5 Suppl 68):S-5-12. Epub 2011 Oct 21.
    Benedek TG.  | http://www.ncbi.nlm.nih.gov/pubmed/22018177
  19. Stress as a risk factor in the pathogenesis of rheumatoid arthritis. Cutolo M, Straub RH. Neuroimmunomodulation. 2006;13(5-6):277-82. Epub 2007 Aug 6. | http://www.ncbi.nlm.nih.gov/pubmed/17709949
  20. Jefferies, William McK. MD. “Safe Uses of Cortisol” 3rd edition Charles C Thomas Publisher. LTD. ISBN 0-398-07501-8
  21. Cortisol, estradiol-17β, and progesterone secretion within the first hour after awakening in women with regular menstrual cycles. Ahn RS, et al. J Endocrinol. 2011 Dec;211(3):285-95. Epub 2011 Sep 29.| http://www.ncbi.nlm.nih.gov/pubmed/21965547
  22. Hans Selye’s General Adaptation Syndrome 1936
  23. Do infants show a cortisol awakening response? Bright MA, et a;. 2011 Oct 17. doi: 10.1002/dev.20617. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/22006547
  24. (Chronobiol Int. 2007;24(5):969-90. Diurnal and seasonal cortisol, testosterone, and DHEA rhythms in boys and girls during puberty.  Matchock RL, Dorn LD, Susman EJ.) | http://www.ncbi.nlm.nih.gov/pubmed?term=17994350
  25. Diurnal cortisol rhythm as a predictor of breast cancer survival. Sephton SE, et al. J Natl Cancer Inst. 2000 Jun 21;92(12):994-1000. http://www.ncbi.nlm.nih.gov/pubmed/10861311
  26. H Burke. Depression and cortisol responses to psychological stress: A meta-analysis.  Psychoneuroendocrinology Vol 30, Iss 9, October 2005 | http://www.sciencedirect.com/science/journal/03064530
  27. Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients. Radsheer FC, et.al. Neuroendocrinology 1994;60:436-444 | http://www.ncbi.nlm.nih.gov/pubmed/10861311
  28. Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression. Radsheer et.al. Am J Psychiatry. 1995; 152:1372-1376 | http://www.ncbi.nlm.nih.gov/pubmed?term=7653697
  29. The neuroendocrinology of chronic fatigue syndrome. Cleare AJ. Endocr Rev. 2003 Apr;24(2):236-52. http://www.ncbi.nlm.nih.gov/pubmed/12700181
  30. Relationship functioning and home and work demands predict individual differences in diurnal cortisol patterns in women. Adam EK, Gunnar MR. Psychoneuroendocrinology. 2001 Feb;26(2):189-208.  | http://www.ncbi.nlm.nih.gov/pubmed/11087964
  31. Cortisol secretion and fatigue: associations in a community based cohort. Kumari M, et al. Psychoneuroendocrinology. 2009 Nov;34(10):1476-85. Epub 2009 Jun 3 |  http://www.ncbi.nlm.nih.gov/pubmed/19497676
  32. Salivary cortisol and sleep problems among civil servants. Hansen AM, et al. Psychoneuroendocrinology. 2011 Dec 29. [Epub ahead of print] | http://www.ncbi.nlm.nih.gov/pubmed/22208999
  33. Effects of dehydroepiandrosterone (DHEA) and lactate on glucose uptake in the central nervous system. de Souza DK, et al. 2012 Jan 17;507(1):62-6. Epub 2011 Dec 6. | http://www.ncbi.nlm.nih.gov/pubmed/22172926
  34. Hormones in Saliva. Vining RF and McGinley RA. Crit Rev in Clin Lab Sci. (1986) 23(2):95-146.
  35. Effect of 1-year, low-dose DHEA therapy on climacteric symptoms and female sexuality. Genazzani AR, et al. Climacteric. 2011 Dec;14(6):661-8. Epub 2011 Sep 26. | http://www.ncbi.nlm.nih.gov/pubmed/21942655
  36. Papadopoulos A.S., Cleara A.J. Nat Rev Endocrinol. 2011 Sep 27
  37. Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial. Hunt PJ, et al. J Clin Endocrinol Metab. 2000 Dec;85(12):4650-6. | http://www.ncbi.nlm.nih.gov/pubmed?term=11134123
  38. Changes in serum sex hormone profiles after short-term low-dose administration of dehydroepiandrosterone (DHEA) to young and elderly persons. Yamada Y, et al. Endocr J. 2007 Feb;54(1):153-62. Epub 2006 Dec 21. |  http://www.ncbi.nlm.nih.gov/pubmed/17185878
  39. Alt Med Review Volume 6, Number 3, 2001
  40. Nestler JE. Insulin and adrenal androgens. Semin Reprod Endocrinol 1994;12:1-5.
  41. Walker, 1971; Pinsky and DiGeorge, 1965; Walker, 1967. 

Women’s Health

  1. Slim, sane and sexy. (Mead and Lommen Calaroga Publishing 2008)
  2. Review of Medical Physiology, Ganong, 22nd ed. 2005 McGraw-Hill. Pp441
  3. Neuroactive steroids: focus on human brain. Melcangi RC, et al. 2011 Sep 15;191:1-5. Epub 2011 Jun 15. Sex steroids and the thyroid. Tahboub R, Arafah BM. Best Pract Res Clin Endocrinol Metab. 2009 Dec;23(6):769-80. | http://www.ncbi.nlm.nih.gov/pubmed/21704130
  4. Speroff, L. (2005). Clinical Hynecologic Endocrinology and Infertility. Philadelphia, PA: Lippincott Williams & Wilkins.
  5. Lemon, HM. Acta Endocrinol (Copenh) 1980;233:S17-S27.
  6. Fournier, A. (2005). Breast cancer risk in relation to different types of hormone replacement therapy in the E3N-EPIC cohort. Int J Cancer, 448-54. | http://www.ncbi.nlm.nih.gov/pubmed?term=15551359
  7. John Lee, M.D. What Your Doctor May Not Tell You About Menopause Jan 2004
  8. John Lee, M.D. Hormone Balance for Men 2003
  9. Sex steroids and the thyroid. Tahboub R, Arafah BM. Best Pract Res Clin Endocrinol Metab. 2009 Dec;23(6):769-80.  | http://www.ncbi.nlm.nih.gov/pubmed?term=19942152
  10. Iodine Replacement in Fibrocystic Disease of the Breast, Ghent, W., Eskin, B., Low, D., Hill, L., Can. J. Surg., 36:453-460, 1993. | http://www.ncbi.nlm.nih.gov/pubmed?term=8221402
  11. Eskin BA. Adv Exp Med Biol. 1977; 91:293-304 | http://www.ncbi.nlm.nih.gov/pubmed?term=343535
  12. Arch Pathol Lab Med 1979 Nov 103(12): 631-4 | http://www.ncbi.nlm.nih.gov/pubmed?term=583121
  13. Can J surg 1993 oct; 36(5):405
  14. Toshihiko Kawamura and Tomotaka Sobue. Comparison of Breast Cancer Mortality in Five Countries: France, Italy, Japan, the UK and the USA from the WHO Mortality Database (1960-2000) Japanese Journal of Clinical Oncology. 2005; 35(12):758-759
  15. J Clin Endocrinol Metab, June 2005, 90(6):3600–3605 3601 | http://www.ncbi.nlm.nih.gov/pubmed?term=15755854
  16. Premenstrual changes and affective disorders. Endicott J, et al. 1981 Dec;43(6):519-29.
  17. Premenstrual syndrome. Dickerson LM, et al. Am Fam Physician. 2003 Apr 15;67(8):1743-52.
  18. Advances in psychiatric treatment  (2001) 7: 469-477 doi: 10.1192/apt.7.6.469 | http://apt.rcpsych.org/content/7/6/469.full
  19. LORI M. DICKERSON, PHARM.D., et.al.  Am Fam Physician. 2003 Apr 15;67(8):1743-1752. http://www.ncbi.nlm.nih.gov/pubmed?term=12725453
  20. T. Hudson, N.D. Women’s Encyclopedia of Natural Medicine 2008
  21. American Cancer Society  2011 http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/breast-cancer-risk-factors
  22. Chang, K. (1995). Influences of Percutaneous Administration of Estradiol and Progesterone on Human Breast Epithelial Cell Cycle in Vivo. Fertil Steril, 64(4): 785-91. | http://www.ncbi.nlm.nih.gov/pubmed?term=7890063
  23. Effectiveness of compounded bioidentical hormone replacement therapy: an observational cohort study. Ruiz AD, et al. BMC Womens Health. 2011 Jun 8;11:27. |  http://www.ncbi.nlm.nih.gov/pubmed?term=21651797
  24. Rigg LA. Estrogen replacement therapy for atrophic vaginitis. Int J Fertil 1986;31(suppl 3):29-34.
  25. Effect of Menopause and Different Combined Estradiol-Progestin Regiments on Basal and Growth Hormone, Insulin-like Growth Factor-1, Insulin-like Growth Factor Binding Protein (IGFBP)-1, and IGFBP-3 Levels. Cano A, Castelo-Branco C, Tarin JJ. Fertil Steril (Feb 1999) 71: 261-7 | http://www.ncbi.nlm.nih.gov/pubmed?term=9988395
  26. Are All Estrogens Created Equal? A Review of Oral vs. Transdermal Therapy. Goodman MP. J Womens Health (Larchmt). 2011 Oct 19.
  27. Writing group of the WHI investigators.  Risks and benefits of estrogen plus progestin in health postmenopausal women. JAMA 17 July 2002; 288: 321-333 | http://www.ncbi.nlm.nih.gov/pubmed?term=2117397

Best Practices For Men’s Hormone Health: from metabolic syndrome to andropause

  1. Koster A, et al. Am J Epidemiol. 2008 Jun 15;167(12):1465-75. Epub 2008 Apr | http://www.ncbi.nlm.nih.gov/pubmed?term=18417494
  2. Gorbachinsky I, Rev Urol 2011;12(4):e157-e180 | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020279/?tool=pubmed
  3. Laukkanen JA etal, Cancer Epidemiol Biomarkers Prev, 2004;13:1646-1650 | http://www.ncbi.nlm.nih.gov/pubmed?term=15466982
  4. Dobs AS and Morgentaler A, Endocrine Practice, Oct 2008, 14 (7):904-10 | http://www.ncbi.nlm.nih.gov/pubmed?term=18996823
  5. Morgentaler A. JAMA 1996;276:1904-6 | http://www.ncbi.nlm.nih.gov/pubmed?term=8968017
  6. Hammarsten J, Hogstedt B. Eur J Cancer 2005 Dec:41(18):2887-95 | http://www.ncbi.nlm.nih.gov/pubmed?term=16243513
  7. Lund Haheim L. et al. Am J Epidemiol 2006 Oct 15;164(8):769-74. | http://www.ncbi.nlm.nih.gov/pubmed?term=16952929
  8. Morely J. E. et al. The Aging Male, Sept 2006; 9(3):165-169 | http://www.ncbi.nlm.nih.gov/pubmed?term=17050116
  9. Patel A, Rivkees SA. Int J Pediatr Endocrinol. 2010; 2010:867471. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952944/?tool=pubmed
  10. C. Brachet, J. Vermeulen, and C. Heinrichs, “Children’s virilization and the use of a testosterone gel by their fathers,” European Journal of Pediatrics, vol. 164, no. 10, pp. 646–647,2005.
  11. E. Cohen, O. M. Navarro, E. Reynolds, R. P. Schwartz, and P. Venkataramani, “Index of suspicion,” Pediatrics in Review, vol. 28, pp. 419–425, 2007.
  12. G. J. Kunz, K. O. Klein, R. D. Clemons, M. E. Gottschalk, and K. L. Jones, “Virilization of young children after topical androgen use by their parents,” Pediatrics, vol. 114, no. 1, pp. 282–284, 2004.
  13. Y. M. Yu, N. Punyasavatsu, D. Elder, and A. J. D’Ercole, “Sexual development in a two-year-old boy induced by topical exposure to testosterone,” Pediatrics, vol. 104, no. 2, p. e23, 1999.
  14. E. L. Rhoden and A. Morgentaler, “Risks of testosteronereplacement therapy and recommendations for monitoring,” New England Journal of Medicine, vol. 350, no. 5, pp. 482–492, 2004.

Belly Fat, Baby Boomers and Boredom in the Bedroom

  1. CDC 2008 | http://www.cdc.gov/obesity/data/trends.HTML
  2. A Koster, NIA, Amer jour of Epidemiol 2008, 167 (12):  1465-1475 | http://www.ncbi.nlm.nih.gov/pubmed?term=18417494
  3. 2009; 119:351-357. Intensive Glycemic Control and the Prevention of Cardiovascular Events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials. A Position Statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association N Engl J Med.  http://www.ncbi.nlm.nih.gov/pubmed/19095622
  4. 2008 Jun 12; 358(24):2545-59. Effects of intensive glucose lowering in type 2 diabetes. Action to Control Cardiovascular Risk in Diabetes Study Group, Gerstein HC, Miller ME, Byington RP, Goff DC Jr, Bigger JT, Buse JB, Cushman WC, Genuth S, Ismail-Beigi F, Grimm RH Jr, Probstfield JL, Simons-Morton DG, Friedewald WT. | http://www.ncbi.nlm.nih.gov/pubmed?term=%3B358(24)%3A2545-59
  5. N Engl J Med. 2002 Feb 7;346(6):393-403. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM; Diabetes Prevention Program Research Group. | http://www.ncbi.nlm.nih.gov/pubmed?term=346(6)%3A393-403
  6. Grimm JJ. Interaction of physical activity and diet: implications for insulin-glucose dynamics. Public Health Nutr 1999;2:363-368 | http://www.ncbi.nlm.nih.gov/pubmed/10610074
  7. (The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group, 2004) http://www.ncbi.nlm.nih.gov/pubmed/14688154
  8. Novak ER Goldberg B Jones GSv Enzyme histochemistry of the menopausal ovary associated with normal and abnormal endometrium.  AM J Obstet 1965;93669-682
  9. WU Atiomo, DPMikhalides, R Morris P Hardiman Royal UK
  10. Br J Nutr. 2005 Aug;94(2):154-65. The optimal diet for women with polycystic ovary syndrome | http://www.ncbi.nlm.nih.gov/pubmed?term=16115348
  11. Effect of High-protein or Normal-protein Diet on Weight Loss, Body Composition, Hormone and Metabolic Profile in Women With Polycystic Ovary Syndrome From South Brazil: A Randomized Study – Clinical Trials NCT01184963
  12. The Natural Diet Solution for PCOS and Infertility – Nancy Dunn, ND
  13. The Anti-Inflammation Diet and Recipe Book – Jessica Black, ND  2006
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